I use Kodi as my HTPC software of choice. In the bedroom I am using a Raspberry Pi 2 running OpenElec which I have had absolutely zero issues with.
As for the living room setup, I can’t say the same.
For this setup, I am using a fairly descent desktop PC as my HTPC which is tucked away behind the bookshelf so it’s out of sight. The PC connects to the TV via a HDMI connection provided by an ATI 5450 card because…well it was cheap and did not have a fan for noise purposes.
The problem that I notice is that approx every hour or so, the audio gets all distorted and tinny and echoes. This happens regardless or what I am using the PC for – some light gaming, but mostly when using Kodi. It’s super annoying when my wife and I are watching a movie and the audio issue pops up.